This journal article describes a study that examined the comparative efficacy of two employment interventions—Social Enterprise Intervention (SEI) and Individual Placement and Support (IPS)—among homeless youth with mental illness. The researchers conducted a randomized controlled trial with participants from a homeless youth agency in Los Angeles: 36 participants in the SEI group and 36 in the IPS group. Over 20 months, SEI participants received four SEI components and IPS participants received IPS services based on eight principles. The study collected data at baseline and follow-up for the primary employment outcome (paid employment) and five secondary employment outcomes. During the reporting period, 39 percent of SEI participants and 32 percent of IPS participants reported any paid employment. Across both groups, participants who reported working at baseline had nearly eight times the odds of working at follow-up. The study did not detect any statistically significant differences across the full sample or between groups on the primary or secondary employment outcomes. The author concludes that future effectiveness research is needed to compare the long-term employment outcomes of the SEI and IPS with a more heterogeneous sample of homeless youth using customized homelessness support services and more nuanced employment outcomes. (author abstract modified)