This guidebook from the US Department of Housing and Urban Development (HUD) is designed for Continuum of Care (CoC) leaders and stakeholders to use as a direct, hands-on action plan in their efforts to prevent and end youth homelessness. This guideline focuses on collaboration efforts by providing strategies to engage mainstream sectors such as child welfare, education, workforce development, justice systems, housing programs, health care providers, community organizations, and federal and state benefit agencies. It includes examples of successful collaboration efforts from across the country.