The National Center for Injury Prevention and Control, under the Centers for Disease Control and Prevention, developed this technical package to help communities and states prioritize prevention activities based on the best available evidence. The three components of this technical package are intended as a resource to guide and inform the prevention decision-making process. First, it provides strategies to strengthen economic supports, improve access and delivery of suicide care, create protective environments, promote connectedness, teach coping and problem-solving skills, identify and support people at risk, and lessen harms and future risk. Second, it provides approaches to advance the strategies through programs, policies, and practices. Third, it supports each approach with evidence about preventing suicide and the associated risk factors. An appendix presents a quick guide to the three components.