This brief identifies five strategies that communities, providers, and policy makers can use to address the intersection of homelessness and the opioid crisis and highlights resources developed by federal and national partners to support such efforts. It includes information about the first-ever report released by the Office of the Surgeon General on this issue called Facing Addiction in America: The Surgeon General’s Report on Alcohol, Drugs, and Health. The brief also includes links to webinars from the National Health Care for the Homeless Council on this topic and a toolkit for law enforcement on naxolone developed by the Department of Justice’s Bureau of Justice Assistance.